Evidence that mitogenic lectins induce changes in lymphocyte membrane fluidity

Ronald E. Barnett, Robert E. Scott, Leo T. Furcht, John H. Kersey

Research output: Contribution to journalArticlepeer-review

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Abstract

MITOGENIC plant lectins, such as phytohaemagglutinin (PHA) and concanavalin A (con A), are useful tools to study the control of cell proliferation in lymphocytes. Recent evidence suggests that these mitogenic lectins trigger mitogenesis at the cell membrane1,2. It is likely that an understanding of the mechanisms by which these lectins stimulate lymphocytes will provide important clues to more general problems of the regulation of proliferation in eukaryotic cells.

Original languageEnglish (US)
Pages (from-to)465-466
Number of pages2
JournalNature
Volume249
Issue number5456
DOIs
StatePublished - Dec 1 1974

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