Evidence for the phagocytic transport of intestinal particles in dogs and rats

C. L. Wells, Michael A Maddaus, S. L. Erlandsen, R. L. Simmons

Research output: Contribution to journalArticle

66 Scopus citations


Fluorescent latex beads of two different colors were implanted into separate intestinal segments in individual dogs and rats. Mesenteric lymph node phagocytes subsequently contained multiple beads of one or the other color but rarely both colors, indicating that intestinal phagocytes transported the latex beads to the draining lymph node. Fluorescent labeled Escherichia coli was implanted into rat ligated intestinal segments, and rare mesenteric lymph node phagocytes subsequently contained fluorescent bacteria, suggesting that intestinal bacteria might be transported in the same manner as inert latex beads.

Original languageEnglish (US)
Pages (from-to)278-282
Number of pages5
JournalInfection and Immunity
Issue number1
StatePublished - Jan 1 1988


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