Evidence for a mechanism predisposing to intergenerational CAG repeat instability in spinocerebellar ataxia type I

Neuroscience

• CAG Repeat 100%
• Spinocerebellar Ataxia 100%
• Neurodegenerative Disorder 50%
• Chromosome 6p 50%
• Trinucleotide Repeat 50%
• Protein Sequencing 50%
• Shotgun Sequencing 50%

Keyphrases

• Spinocerebellar Ataxia 100%
• CAG Repeat Instability 100%
• Repeat number 60%
• Neurodegenerative Diseases 20%
• Sequence Analysis 20%
• Autosomal Dominant 20%
• Chromosome 6p 20%
• Paternal Transmission 20%
• Maternal Transmission 20%
• Repeat Instability 20%
• CAG Trinucleotide Repeat 20%

Biochemistry, Genetics and Molecular Biology

• Allele 100%
• CAG Repeat 100%
• Trinucleotide Repeat Expansion 25%
• Protein Sequencing 25%
• Autosomal Dominant Inheritance 25%
• Chromosome 6p 25%
• Shotgun Sequencing 25%