Event-related FMRI analysis of the cerebral circuit for number comparison

Philippe Pinel, Gurvan Le Clec'H, Pierre Francois Van De Moortele, Lionel Naccache, Denis Le Bihan, Stanislas Dehaene

Research output: Contribution to journalArticlepeer-review

136 Scopus citations

Abstract

Cerebral activity during number comparison was studied with functional magnetic resonance imaging using an event-related design. We identified an extended network of task-related areas that showed a phasic activation following each trial, including anterior cingulate, bilateral sensorimotor areas, inferior occipitotemporal cortices, posterior parietal cortices, inferior and dorsolateral prefrontal cortices, and thalami. We then tested which of these areas were affected by number notation, numerical distance and response side, three variables that specifically target processes of visual identification, quantity manipulation and motor response in a serial-stage model of the number comparison task. Our results confirm the role of the right fusiform gyrus in digit identification processes, and of the inferior parietal lobule in the internal manipulation of numerical quantities.

Original languageEnglish (US)
Pages (from-to)1473-1479
Number of pages7
JournalNeuroreport
Volume10
Issue number7
DOIs
StatePublished - May 14 1999

Keywords

  • Arithmetic
  • Distance effect
  • Fusiform gyrus
  • Parietal cortex

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