Evaluations of labrador retrieverswith exercise-induced collapse, including response to a standardized strenuous exercise protocol

Susan M. Taylor, Cindy L. Shmon, Vicki J. Adams, James R. Mickelson, Edward E. Patterson, G. Diane Shelton

Research output: Contribution to journalArticlepeer-review

18 Scopus citations

Abstract

Clinical and metabolic variables were evaluated in 14 Labrador retrievers with exerciseinduced collapse (EIC) before, during, and following completion of a standardized strenuous exercise protocol. Findings were compared with previously reported variables from 14 normal Labrador retrievers that participated in the same protocol. Ten of 14 dogs with EIC developed an abnormal gait during evaluation, and these dogs were significantly more tachycardic and had a more severe respiratory alkalosis after exercise compared to the normal dogs. Muscle biopsy characteristics and sequential lactate and pyruvate concentrations were normal. Genetic testing and linkage analysis excluded malignant hyperthermia as the cause of EIC. Common causes of exercise intolerance were eliminated, but the cause of collapse in EIC was not determined.

Original languageEnglish (US)
Pages (from-to)3-13
Number of pages11
JournalJournal of the American Animal Hospital Association
Volume45
Issue number1
DOIs
StatePublished - 2009

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