Evaluation of the efficacy of a bioerodible bupivacaine polymer system on antinociception and inflammatory mediator release

Keyphrases

• Polymer System 100%
• Bupivacaine 100%
• Inflammatory Mediators 100%
• Antinociception 100%
• Mediator Release 100%
• Bioerodible 100%
• Bioerodible Polymer 50%
• Inflammation 33%
• Hyperalgesia 33%
• Substance P 33%
• Primary Afferent 33%
• Bradykinin 33%
• Hind Paw 33%
• Afferent Input 33%
• Central Nervous System 16%
• Potential Therapeutics 16%
• Hyperthermia 16%
• Awake Animal 16%
• Drug Dosing 16%
• Inhibitory Effect 16%
• Controlled Drug Delivery 16%
• Systemic Side Effects 16%
• Edema 16%
• Local Application 16%
• Total Drug 16%
• Tissue Injury 16%
• Tissue Compartments 16%
• Freund Incomplete Adjuvant 16%
• Tissue Level 16%
• Inflamed Tissue 16%
• Allodynia 16%
• Therapeutic Utility 16%
• Edema Index 16%
• Inflammatory Hyperalgesia 16%
• Perceptual State 16%
• Primary Afferent Neuron 16%
• Preemptive Analgesia 16%
• Biochemical Indices 16%
• Local Anesthetics 16%
• Single-dose Treatment 16%

Pharmacology, Toxicology and Pharmaceutical Science

• Antinociception 100%
• Bupivacaine 100%
• Hyperalgesia 50%
• Inflammation 33%
• Substance P 33%
• Edema 33%
• Bradykinin 33%
• Drug Dose 16%
• Local Anesthetic Agent 16%
• Side Effect 16%
• Hyperthermia 16%
• Tissue Injury 16%
• Allodynia 16%
• Controlled Substance 16%
• Freund's Adjuvant 16%