Evaluation of the economic impact of modified screening criteria for retinopathy of prematurity from the Postnatal Growth and ROP (G-ROP) study

the G-ROP Study Group

doi:10.1038/s41372-020-0605-5

Evaluation of the economic impact of modified screening criteria for retinopathy of prematurity from the Postnatal Growth and ROP (G-ROP) study

the G-ROP Study Group

Ophthalmology & Visual Neurosciences

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

IMPORTANCE: The Postnatal Growth and Retinopathy of Prematurity (G-ROP) Study showed that the addition of postnatal weight gain to birth weight and gestational age detects similar numbers of infants with ROP, but requires examination of fewer infants.

OBJECTIVE: To determine the incremental cost-effectiveness of screening with G-ROP compared with conventional screening.

DESIGN, SETTING AND PARTICIPANTS: We built a microsimulation model of a 1-year US birth cohort <32 weeks gestation, using data from the G-ROP study. We obtained resource utilization estimates from the G-ROP dataset and from secondary sources, and test characteristics from the G-ROP cohort.

RESULTS: Among 78,281 infants nationally, screening with G-ROP detected ~25 additional infants with Type 1 ROP. This was accomplished with 36,233 fewer examinations, in 14,073 fewer infants, with annual cost savings of approximately US$2,931,980 through hospital discharge.

CONCLUSIONS: Screening with G-ROP reduced costs while increasing the detection of ROP compared with current screening guidelines.

Original language	English (US)
Pages (from-to)	1100-1108
Number of pages	9
Journal	Journal of Perinatology
Volume	40
Issue number	7
DOIs	https://doi.org/10.1038/s41372-020-0605-5
State	Published - Jul 1 2020

Bibliographical note

Funding Information:
Funding This study was supported by the National Institutes of Health grant R01EY021137, and the Richard Shafritz Endowed Chair in Ophthalmology Research at the Children’s Hospital of Philadelphia.

Publisher Copyright:
© 2020, The Author(s), under exclusive licence to Springer Nature America, Inc.

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@article{ce428db6b5ff4549a838032f711b2ffd,

title = "Evaluation of the economic impact of modified screening criteria for retinopathy of prematurity from the Postnatal Growth and ROP (G-ROP) study",

abstract = "IMPORTANCE: The Postnatal Growth and Retinopathy of Prematurity (G-ROP) Study showed that the addition of postnatal weight gain to birth weight and gestational age detects similar numbers of infants with ROP, but requires examination of fewer infants.OBJECTIVE: To determine the incremental cost-effectiveness of screening with G-ROP compared with conventional screening.DESIGN, SETTING AND PARTICIPANTS: We built a microsimulation model of a 1-year US birth cohort <32 weeks gestation, using data from the G-ROP study. We obtained resource utilization estimates from the G-ROP dataset and from secondary sources, and test characteristics from the G-ROP cohort.RESULTS: Among 78,281 infants nationally, screening with G-ROP detected ~25 additional infants with Type 1 ROP. This was accomplished with 36,233 fewer examinations, in 14,073 fewer infants, with annual cost savings of approximately US$2,931,980 through hospital discharge.CONCLUSIONS: Screening with G-ROP reduced costs while increasing the detection of ROP compared with current screening guidelines.",

author = "{the G-ROP Study Group} and Zupancic, {John A.F.} and Ying, {Gui shuang} and {de Alba Campomanes}, Alejandra and Tomlinson, {Lauren A.} and Gil Binenbaum and Gil Binenbaum and Tomlinson, {Lauren A.} and Duros, {Trang B.} and Anh Nguyen and Ying, {Gui shuang} and Maguire, {Maureen G.} and Mary Brightwell-Arnold and James Shaffer and Yinxi Yu and Maria Blanco and Trina Brown and Helker, {Christopher P.} and Amy Hutchinson and Carrie Young and Emily McCourt and Anne Lynch and Jennifer Cathcart and Ashlee Cerda and Levi Bonnell and Tamara Thevarajah and Barry, {Gerard P.} and Marilyn Fisher and Battaglia, {Maria V.} and Drach, {Alex M.} and Kevin Hughes and Nachammai Chinnakaruppan and Andrew Meyer and Christina Gogal and Cynthia Beitler and Lauri Centolanza and Moyer, {Keith T.} and Mary Sobotor and Pamela Donohue and Repka, {Michael X.} and Shepard, {Jennifer A.} and Megan Doherty and Reynolds, {James D.} and Erin Connelly and Edward Cheeseman and Kinsey Shirer and Carol Bradham and Allison McAlpine and Jill Anderson and Areaux, {Raymond G.} and Holleschau, {Ann Marie}",

note = "Funding Information: Funding This study was supported by the National Institutes of Health grant R01EY021137, and the Richard Shafritz Endowed Chair in Ophthalmology Research at the Children{\textquoteright}s Hospital of Philadelphia. Publisher Copyright: {\textcopyright} 2020, The Author(s), under exclusive licence to Springer Nature America, Inc.",

year = "2020",

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doi = "10.1038/s41372-020-0605-5",

language = "English (US)",

volume = "40",

pages = "1100--1108",

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T1 - Evaluation of the economic impact of modified screening criteria for retinopathy of prematurity from the Postnatal Growth and ROP (G-ROP) study

AU - the G-ROP Study Group

AU - Zupancic, John A.F.

AU - Ying, Gui shuang

AU - de Alba Campomanes, Alejandra

AU - Tomlinson, Lauren A.

AU - Binenbaum, Gil

AU - Tomlinson, Lauren A.

AU - Duros, Trang B.

AU - Nguyen, Anh

AU - Ying, Gui shuang

AU - Maguire, Maureen G.

AU - Brightwell-Arnold, Mary

AU - Shaffer, James

AU - Yu, Yinxi

AU - Blanco, Maria

AU - Brown, Trina

AU - Helker, Christopher P.

AU - Hutchinson, Amy

AU - Young, Carrie

AU - McCourt, Emily

AU - Lynch, Anne

AU - Cathcart, Jennifer

AU - Cerda, Ashlee

AU - Bonnell, Levi

AU - Thevarajah, Tamara

AU - Barry, Gerard P.

AU - Fisher, Marilyn

AU - Battaglia, Maria V.

AU - Drach, Alex M.

AU - Hughes, Kevin

AU - Chinnakaruppan, Nachammai

AU - Meyer, Andrew

AU - Gogal, Christina

AU - Beitler, Cynthia

AU - Centolanza, Lauri

AU - Moyer, Keith T.

AU - Sobotor, Mary

AU - Donohue, Pamela

AU - Repka, Michael X.

AU - Shepard, Jennifer A.

AU - Doherty, Megan

AU - Reynolds, James D.

AU - Connelly, Erin

AU - Cheeseman, Edward

AU - Shirer, Kinsey

AU - Bradham, Carol

AU - McAlpine, Allison

AU - Anderson, Jill

AU - Areaux, Raymond G.

AU - Holleschau, Ann Marie

N1 - Funding Information: Funding This study was supported by the National Institutes of Health grant R01EY021137, and the Richard Shafritz Endowed Chair in Ophthalmology Research at the Children’s Hospital of Philadelphia. Publisher Copyright: © 2020, The Author(s), under exclusive licence to Springer Nature America, Inc.

PY - 2020/7/1

Y1 - 2020/7/1

N2 - IMPORTANCE: The Postnatal Growth and Retinopathy of Prematurity (G-ROP) Study showed that the addition of postnatal weight gain to birth weight and gestational age detects similar numbers of infants with ROP, but requires examination of fewer infants.OBJECTIVE: To determine the incremental cost-effectiveness of screening with G-ROP compared with conventional screening.DESIGN, SETTING AND PARTICIPANTS: We built a microsimulation model of a 1-year US birth cohort <32 weeks gestation, using data from the G-ROP study. We obtained resource utilization estimates from the G-ROP dataset and from secondary sources, and test characteristics from the G-ROP cohort.RESULTS: Among 78,281 infants nationally, screening with G-ROP detected ~25 additional infants with Type 1 ROP. This was accomplished with 36,233 fewer examinations, in 14,073 fewer infants, with annual cost savings of approximately US$2,931,980 through hospital discharge.CONCLUSIONS: Screening with G-ROP reduced costs while increasing the detection of ROP compared with current screening guidelines.

AB - IMPORTANCE: The Postnatal Growth and Retinopathy of Prematurity (G-ROP) Study showed that the addition of postnatal weight gain to birth weight and gestational age detects similar numbers of infants with ROP, but requires examination of fewer infants.OBJECTIVE: To determine the incremental cost-effectiveness of screening with G-ROP compared with conventional screening.DESIGN, SETTING AND PARTICIPANTS: We built a microsimulation model of a 1-year US birth cohort <32 weeks gestation, using data from the G-ROP study. We obtained resource utilization estimates from the G-ROP dataset and from secondary sources, and test characteristics from the G-ROP cohort.RESULTS: Among 78,281 infants nationally, screening with G-ROP detected ~25 additional infants with Type 1 ROP. This was accomplished with 36,233 fewer examinations, in 14,073 fewer infants, with annual cost savings of approximately US$2,931,980 through hospital discharge.CONCLUSIONS: Screening with G-ROP reduced costs while increasing the detection of ROP compared with current screening guidelines.

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U2 - 10.1038/s41372-020-0605-5

DO - 10.1038/s41372-020-0605-5

M3 - Article

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AN - SCOPUS:85081324359

SN - 0743-8346

VL - 40

SP - 1100

EP - 1108

JO - Journal of Perinatology

JF - Journal of Perinatology

IS - 7

ER -

Evaluation of the economic impact of modified screening criteria for retinopathy of prematurity from the Postnatal Growth and ROP (G-ROP) study

Abstract

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