Evaluation of the Boussignac Cardiac arrest device (B-card) during cardiopulmonary resuscitation in an animal model

Johanna C. Moore, Lionel Lamhaut, Alice Hutin, Kenneth W. Dodd, Aaron E. Robinson, Michael C. Lick, Bayert J. Salverda, Mason B. Hinke, Jose Larabere, Guillaume Debaty, Nicolas Segal

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


Aim of the study The purpose of this study was to examine continuous oxygen insufflation (COI) in a swine model of cardiac arrest. The primary hypothesis was COI during standard CPR (S-CPR) should result in higher intrathoracic pressure (ITP) during chest compression and lower ITP during decompression versus S-CPR alone. These changes with COI were hypothesized to improve hemodynamics. The second hypothesis was that changes in ITP with S-CPR + COI would result in superior hemodynamics compared with active compression decompression (ACD) + impedance threshold device (ITD) CPR, as this method primarily lowers ITP during chest decompression. Methods After 6 min of untreated ventricular fibrillation, S-CPR was initiated in 8 female swine for 4 min, then 3 min of S-CPR + COI, then 3 min of ACD + ITD CPR, then 3 min of S-CPR + COI. ITP and hemodynamics were continuously monitored. Results During S-CPR + COI, ITP was always positive during the CPR compression and decompression phases. ITP compression values with S-CPR + COI versus S-CPR alone were 5.5 ± 3 versus 0.2 ± 2 (p < 0.001) and decompression values were 2.8 ± 2 versus −1.3 ± 2 (p < 0.001), respectively. With S-CPR + COI versus ACD + ITD the ITP compression values were 5.5 ± 3 versus 1.5 ± 2 (p < 0.01) and decompression values were 2.8 ± 2 versus −4.7 ± 3 (p < 0.001), respectively. Conclusion COI during S-CPR created a continuous positive pressure in the airway during both the compression and decompression phase of CPR. At no point in time did COI generate a negative intrathoracic pressures during CPR in this swine model of cardiac arrest.

Original languageEnglish (US)
Pages (from-to)81-88
Number of pages8
StatePublished - Oct 2017

Bibliographical note

Publisher Copyright:
© 2017 Elsevier B.V.


  • *Insufflation/instrumentation
  • Active compression decompression
  • Animals
  • B-card
  • Boussignac
  • Cardiac arrest
  • Cardiopulmonary resuscitation
  • Heart arrest/drug therapy/physiopathology/*therapy
  • Hemodynamics impedance threshold device
  • Oxygen/*administration & dosage
  • Swine
  • Ventricular fibrillation/*therapy


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