Evaluation of the binding constants, bound chemical shifts, and equilibrium stoichiometry for the association of lanthanide shift reagents with carbohydrate derivatives

Anita Arduini; Ian M. Armitage; Laurance D. Hall; Alan G. Marshall

doi:10.1016/S0008-6215(00)86190-X

Evaluation of the binding constants, bound chemical shifts, and equilibrium stoichiometry for the association of lanthanide shift reagents with carbohydrate derivatives

Anita Arduini
, Ian M. Armitage
, Laurance D. Hall
, Alan G. Marshall

Biochemistry, Molecular Biology, and Biophysics (TMED)

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

The molecular associations of tris(dipivalomethanato)europium(III) (1) and of tris(2,2-dimethyl-6,6,7,7,8,8,8,-heptafluoro-3,5-octanedionato)europium(III) (2) with six carbohydrate derivatives have been studied. The interactions of 2 in deuterochloroform solution appear to be "normal", i.e., the plot of [sugar concentration] versus [induced chemical-shift change]^-1 is linear and can be interpreted in terms of the equilibrium binding constant (K_B) and the bound chemical shifts (°_B). Similar results are found for 1 in carbon tetrachloride solutions. However, in chloroform solutions, non-linear plots are obtained that cannot be simply interpreted. Possible reasons for this behaviour are given.

Original language	English (US)
Pages (from-to)	255-263
Number of pages	9
Journal	Carbohydrate Research
Volume	31
Issue number	2
DOIs	https://doi.org/10.1016/S0008-6215(00)86190-X
State	Published - Dec 1973

Bibliographical note

Funding Information:
This work was supported by operating grants from the National Research Council of Canada (A 1905 to L. D. H. and A 6178 to A. G. M.), and by funds from the Alfred P. Sloan Foundation.

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10.1016/S0008-6215(00)86190-X

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title = "Evaluation of the binding constants, bound chemical shifts, and equilibrium stoichiometry for the association of lanthanide shift reagents with carbohydrate derivatives",

abstract = "The molecular associations of tris(dipivalomethanato)europium(III) (1) and of tris(2,2-dimethyl-6,6,7,7,8,8,8,-heptafluoro-3,5-octanedionato)europium(III) (2) with six carbohydrate derivatives have been studied. The interactions of 2 in deuterochloroform solution appear to be {"}normal{"}, i.e., the plot of [sugar concentration] versus [induced chemical-shift change]-1 is linear and can be interpreted in terms of the equilibrium binding constant (KB) and the bound chemical shifts (°B). Similar results are found for 1 in carbon tetrachloride solutions. However, in chloroform solutions, non-linear plots are obtained that cannot be simply interpreted. Possible reasons for this behaviour are given.",

author = "Anita Arduini and Armitage, \{Ian M.\} and Hall, \{Laurance D.\} and Marshall, \{Alan G.\}",

note = "Funding Information: This work was supported by operating grants from the National Research Council of Canada (A 1905 to L. D. H. and A 6178 to A. G. M.), and by funds from the Alfred P. Sloan Foundation.",

year = "1973",

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doi = "10.1016/S0008-6215(00)86190-X",

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T1 - Evaluation of the binding constants, bound chemical shifts, and equilibrium stoichiometry for the association of lanthanide shift reagents with carbohydrate derivatives

AU - Arduini, Anita

AU - Armitage, Ian M.

AU - Hall, Laurance D.

AU - Marshall, Alan G.

N1 - Funding Information: This work was supported by operating grants from the National Research Council of Canada (A 1905 to L. D. H. and A 6178 to A. G. M.), and by funds from the Alfred P. Sloan Foundation.

PY - 1973/12

Y1 - 1973/12

N2 - The molecular associations of tris(dipivalomethanato)europium(III) (1) and of tris(2,2-dimethyl-6,6,7,7,8,8,8,-heptafluoro-3,5-octanedionato)europium(III) (2) with six carbohydrate derivatives have been studied. The interactions of 2 in deuterochloroform solution appear to be "normal", i.e., the plot of [sugar concentration] versus [induced chemical-shift change]-1 is linear and can be interpreted in terms of the equilibrium binding constant (KB) and the bound chemical shifts (°B). Similar results are found for 1 in carbon tetrachloride solutions. However, in chloroform solutions, non-linear plots are obtained that cannot be simply interpreted. Possible reasons for this behaviour are given.

AB - The molecular associations of tris(dipivalomethanato)europium(III) (1) and of tris(2,2-dimethyl-6,6,7,7,8,8,8,-heptafluoro-3,5-octanedionato)europium(III) (2) with six carbohydrate derivatives have been studied. The interactions of 2 in deuterochloroform solution appear to be "normal", i.e., the plot of [sugar concentration] versus [induced chemical-shift change]-1 is linear and can be interpreted in terms of the equilibrium binding constant (KB) and the bound chemical shifts (°B). Similar results are found for 1 in carbon tetrachloride solutions. However, in chloroform solutions, non-linear plots are obtained that cannot be simply interpreted. Possible reasons for this behaviour are given.

UR - https://www.scopus.com/pages/publications/0040028060

UR - https://www.scopus.com/pages/publications/0040028060#tab=citedBy

U2 - 10.1016/S0008-6215(00)86190-X

DO - 10.1016/S0008-6215(00)86190-X

M3 - Article

AN - SCOPUS:0040028060

SN - 0008-6215

VL - 31

SP - 255

EP - 263

JO - Carbohydrate Research

JF - Carbohydrate Research

IS - 2

ER -

Evaluation of the binding constants, bound chemical shifts, and equilibrium stoichiometry for the association of lanthanide shift reagents with carbohydrate derivatives

Abstract

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