Evaluation of rapid diagnostic tests for assessment of hepatitis b in resource-limited settings

James S. Leathers; M. Belen Pisano; Viviana Re; Gertine van Oord; Amir Sultan; Andre Boonstra; Jose D. Debes

doi:10.5334/aogh.2562

Evaluation of rapid diagnostic tests for assessment of hepatitis b in resource-limited settings

James S. Leathers, M. Belen Pisano, Viviana Re, Gertine van Oord, Amir Sultan, Andre Boonstra, Jose D. Debes

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9 Scopus citations

Abstract

Chronic Hepatitis B (HBV) is the most important cause of liver disease worldwide. There is a need for low-cost tests to aid in diagnosis and management of HBV infection in resource-limited settings. We evaluated the utility of several rapid diagnostic tests (RDT) in three different continents (Europe, South America, Africa). The HBsAg RDT showed optimal sensitivity and specificity. The anti-HBeAb RDT showed acceptable sensitivity and excellent specificity. Our results suggest that these RDTs could be used for screening and management of HBV.

Original language	English (US)
Article number	98
Journal	Annals of global health
Volume	85
Issue number	1
DOIs	https://doi.org/10.5334/aogh.2562
State	Published - 2019

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© 2019, Ubiquity Press. All rights reserved.

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AU - Re, Viviana

AU - Oord, Gertine van

AU - Sultan, Amir

AU - Boonstra, Andre

AU - Debes, Jose D.

PY - 2019

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AB - Chronic Hepatitis B (HBV) is the most important cause of liver disease worldwide. There is a need for low-cost tests to aid in diagnosis and management of HBV infection in resource-limited settings. We evaluated the utility of several rapid diagnostic tests (RDT) in three different continents (Europe, South America, Africa). The HBsAg RDT showed optimal sensitivity and specificity. The anti-HBeAb RDT showed acceptable sensitivity and excellent specificity. Our results suggest that these RDTs could be used for screening and management of HBV.

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Evaluation of rapid diagnostic tests for assessment of hepatitis b in resource-limited settings

Abstract

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