Evaluation of Irradiated Mandibles Using Emission Tomography, Bone Scans, and Radiography

Michael D. Rohrer, Louis T. Kircos, James H. Thrall, Young Kim, Juan V. Fayos

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


This study compared radiographs, bone scans, and computed emission tomograms with histologic findings in irradiated mandibles of adult Rhesus monkeys. Although osteocytes were lost in the path of the beam, many vessels were partially or totally occluded, the periosteum degenerated, the marrow became fibrotic, and cancellous bone proliferated abundantly, no changes were noted with radiography, conventional bone scanning, or computed emission tomograms. These clinical methods of examination may misrepresent the true condition of irradiated bone because of inadequate sensitivity or balance among factors that control radioactive tracer uptake in bone.

Original languageEnglish (US)
Pages (from-to)2032-2037
Number of pages6
JournalJournal of dental research
Issue number12
StatePublished - Dec 1980
Externally publishedYes


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