European Heart Rhythm Association (EHRA)/Heart Rhythm Society (HRS)/Asia Pacific Heart Rhythm Society (APHRS)/Latin American Heart Rhythm Society (LAHRS) expert consensus on arrhythmias and cognitive function: what is the best practice?

Nikolaos Dagres, Tze Fan Chao, Guilherme Fenelon, Luis Aguinaga, Daniel Benhayon, Emelia J. Benjamin, T. Jared Bunch, Lin Yee Chen, Shih Ann Chen, Francisco Darrieux, Angelo de Paola, Laurent Fauchier, Andreas Goette, Jonathan Kalman, Lalit Kalra, Young Hoon Kim, Deirdre A. Lane, Gregory Y.H. Lip, Steven A. Lubitz, Manlio F. MárquezTatjana Potpara, Domingo Luis Pozzer, Jeremy N. Ruskin, Irina Savelieva, Wee Siong Teo, Hung Fat Tse, Atul Verma, Shu Zhang, Mina K. Chung

Research output: Contribution to journalArticlepeer-review

20 Scopus citations
Original languageEnglish (US)
Pages (from-to)e37-e60
JournalHeart Rhythm
Issue number6
StatePublished - Jun 2018

Bibliographical note

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Unfortunately there are no randomized data examining the efficacy of therapies and in particular of individualized management to prevent dementia in individuals with AF.57 Of interest, the Framingham Heart Study has examined temporal trends in the incidence of dementia and noted that the risk of dementia associated with AF declined over three decades (1970s to the early 2010s).58 One speculation is that improved anticoagulation and treatment of risk factors were responsible for the declining incidence of dementia in individuals with AF. Another piece of inferential evidence, supporting the benefit of preventing stroke as a strategy to prevent dementia in individuals with AF, are observational meta-analyses (Table 6). In individuals with AF but without stroke at baseline the risk of dementia and cognitive decline is more modest [relative risk (RR) 1.37, 95% confidence interval (CI) 1.08–1.73] than in individuals with both AF and a history of stroke (RR 2.7, 95% CI 1.82–4.00).25


  • Arrythmias
  • Asia Pacific Heart Rhythm Society
  • Cognitive
  • Dementia
  • European Heart Rhythm Association
  • Heart Rhythm Society
  • Latin American Heart Rhythm Society

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