Original language | English (US) |
---|---|
Pages (from-to) | e37-e60 |
Journal | Heart Rhythm |
Volume | 15 |
Issue number | 6 |
DOIs | |
State | Published - Jun 2018 |
Bibliographical note
Funding Information:Unfortunately there are no randomized data examining the efficacy of therapies and in particular of individualized management to prevent dementia in individuals with AF.57 Of interest, the Framingham Heart Study has examined temporal trends in the incidence of dementia and noted that the risk of dementia associated with AF declined over three decades (1970s to the early 2010s).58 One speculation is that improved anticoagulation and treatment of risk factors were responsible for the declining incidence of dementia in individuals with AF. Another piece of inferential evidence, supporting the benefit of preventing stroke as a strategy to prevent dementia in individuals with AF, are observational meta-analyses (Table 6). In individuals with AF but without stroke at baseline the risk of dementia and cognitive decline is more modest [relative risk (RR) 1.37, 95% confidence interval (CI) 1.08–1.73] than in individuals with both AF and a history of stroke (RR 2.7, 95% CI 1.82–4.00).25
Keywords
- Arrythmias
- Asia Pacific Heart Rhythm Society
- Cognitive
- Dementia
- European Heart Rhythm Association
- Heart Rhythm Society
- Latin American Heart Rhythm Society