Abstract
Maximum Likelihood Estimation of order and treatment effects are derived for Binomial Crossover Designs. All estimators and estimated covariance and variances have closed forms and can be easily evaluated. These results are useful for use in multi‐center clinical trials.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 167-171 |
| Number of pages | 5 |
| Journal | Biometrical Journal |
| Volume | 26 |
| Issue number | 2 |
| DOIs | |
| State | Published - 1984 |
Keywords
- Binomial Crossover Design
- Estimation of Parameters
- Multi‐center Clinical Trials