Esophageal stenting and radiotherapy: A multimodal approach for the palliation of symptomatic malignant dysphagia

Natasha M. Rueth, Darcy Shaw, Jonathan D'Cunha, L. Chinsoo Cho, Michael A Maddaus, Rafael S Andrade

Research output: Contribution to journalReview article

15 Scopus citations

Abstract

Background. Esophageal stents provide immediate palliation of malignant dysphagia; however, radiotherapy (RT) is a superior long-term option. We review the outcomes of combined esophageal stenting and RT for patients with malignant dysphagia. Methods. We retrospectively reviewed patients with esophageal stents placed for palliation of malignant dys-phagia from esophageal stricture, esophageal extrinsic compression, or malignant tracheoesophageal fistula (TEF). We excluded patients with radiation-induced TEF in the absence of tumor. We analyzed and compared outcomes between patients with no RT, RT before stent placement, and RT after stent placement. Results. We placed stents in 45 patients for esophageal stricture from esophageal cancer (n = 30; 66.7 %), malignant TEF (n = 8; 17.7 %), and esophageal compression from airway, mediastinal, or metastatic malignancies (n = 7; 15.6 %). Twenty patients (44.4 %) had no RT; 25 patients had RT before stent placement (n = 16; 35.6 %), RT after stent placement (n = 8; 17.8 %), or both (n = 1; 2.2 %). Median follow-up was 30 days. Complications requiring stent revision were similar with or without RT. Subjective symptom relief was achieved in 68.9 % of all patients, with no differences noted between groups (p = 0.99). The 30-day mortality was 15.6 %. Patients with RT after stent placement had a longer median survival compared to those without RT (98 vs. 38 days). Conclusions. Esophageal stent placement with RT is a safe approach for malignant dysphagia.

Original languageEnglish (US)
Pages (from-to)4223-4228
Number of pages6
JournalAnnals of Surgical Oncology
Volume19
Issue number13
DOIs
StatePublished - Dec 1 2012

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