Erratum: Single-cell analysis reveals different age-related somatic mutation profiles between stem and differentiated cells in human liver (Science Advances DOI: 10.1126/sciadv.aax2659)

K. Brazhnik, S. Sun, O. Alani, M. Kinkhabwala, A. W. Wolkoff, A. Y. Maslov, X. Dong, J. Vijg

Research output: Contribution to journalComment/debatepeer-review

Abstract

In the article “Single-cell analysis reveals different age-related somatic mutation profiles between stem and differentiated cells in human liver,” as a result of a mix-up between the single cells and the bulk controls, the authors erroneously claimed four outlier cells. Upon reanalysis, the authors have concluded that there are no real outliers. Additional mutations thought to be bona fide de novo somatic mutations were SNPs due to the wrong bulk control. The main text, Figs. 1-2, supplementary material, and tables S2-5 have been updated.

Original languageEnglish (US)
Article numbereabe8055
JournalScience Advances
Volume6
Issue number40
DOIs
StatePublished - Sep 30 2020
Externally publishedYes

Bibliographical note

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© 2020, American Association for the Advancement of Science

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