Erectile dysfunction is highly prevalent in men with newly diagnosed inflammatory bowel disease

E. Shmidt, M. Suárez-Fariñas, M. Mallette, H. Moniz, R. Bright, S. A. Shah, M. Merrick, J. Shapiro, F. Xu, S. Saha, B. E. Sands

Research output: Contribution to journalArticlepeer-review

22 Scopus citations


Background and Aims: Cross-sectional studies on sexual function in men with inflammatory bowel disease (IBD) yield mixed results. Using a prospective incidence cohort, we aimed to describe sexual function at baseline and over time and to identify factors associated with impaired sexual function in men with IBD. Methods: Men 18 years and older enrolled between April 2008 and January 2013 in the Ocean State Crohn's and Colitis Area Registry (OSCCAR) with a minimum of 2 years of follow-up were eligible for study. Male sexual function was assessed using the International Index of Erectile Function (IIEF), a self-administered questionnaire that assesses 5 dimensions of sexual function over the most recent 4 weeks. To assess changes in the IIEF per various demographic and clinical factors, linear mixed effects models were used. Results: Sixty-nine of 82 eligible men (84%) completed the questionnaire (41 Crohn's disease, 28 ulcerative colitis). The mean age (SD) of the cohort at diagnosis was 43.4 (19.2) years. At baseline, 39% of men had global sexual dysfunction, and 94% had erectile dysfunction. Independent factors associated with erectile dysfunction are older age and lower physical and mental component summary scores on the Short Form Health Survey (SF-36). Conclusion: In an incident cohort of IBD patients, most men had erectile dysfunction. Physicians should be aware of the high prevalence of erectile dysfunction and its associated risk factors among men with newly diagnosed IBD to direct multidisciplinary treatment planning.

Original languageEnglish (US)
Pages (from-to)1408-1416
Number of pages9
JournalInflammatory bowel diseases
Issue number8
StatePublished - Jul 17 2019

Bibliographical note

Funding Information:
This work was supported by grants from the Center for Disease Control and Prevention (CDC) (5U01DP000340 and 3U01DP002676) and the Crohn's and Colitis Foundation of America (CCFA). The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the Centers for Disease Control and Prevention.

Publisher Copyright:
© 2019 Crohn's & Colitis Foundation. Published by Oxford University Press. All rights reserved.


  • Crohn's disease
  • Quality of life
  • Sexual function
  • Ulcerative colitis


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