Abstract
Epstein-Barr virus (EBV) is a ubiquitous human pathogen that infects >90% of adults worldwide. EBV is responsible for most cases of infectious mononucleosis, and is associated with the development of certain cancers and autoimmune diseases, especially multiple sclerosis. EBV vaccines could potentially eliminate or reduce the severity of all of these diseases. This chapter reviews the research on prophylactic and therapeutic EBV vaccines including a discussion of the barriers impacting their development.
| Original language | English (US) |
|---|---|
| Title of host publication | Plotkin's Vaccines, Eighth Edition |
| Publisher | Elsevier |
| Pages | 341-347 |
| Number of pages | 7 |
| ISBN (Electronic) | 9780323790581 |
| ISBN (Print) | 9780323790604 |
| DOIs | |
| State | Published - Jan 1 2023 |
Bibliographical note
Publisher Copyright:© 2023 Elsevier Inc. All rights reserved.
Keywords
- Burkitt lymphoma
- EBV vaccine
- Epstein-Barr virus
- Hodgkin lymphoma
- infectious mononucleosis
- multiple sclerosis
- nasopharyngeal carcinoma
- post-transplant lymphoproliferative disorder