Epstein-Barr virus and host cell 3D genome organization

Chong Wang, Bo Zhao

Research output: Contribution to journalReview articlepeer-review


The human genome is organized in an extremely complexed yet ordered way within the nucleus. Genome organization plays a critical role in the regulation of gene expression. Viruses manipulate the host machinery to influence host genome organization to favor their survival and promote disease development. Epstein-Barr virus (EBV) is a common human virus, whose infection is associated with various diseases, including infectious mononucleosis, cancer, and autoimmune disorders. This review summarizes our current knowledge of how EBV uses different strategies to control the cellular 3D genome organization to affect cell gene expression to transform normal cells into lymphoblasts.

Original languageEnglish (US)
Article numbere29234
JournalJournal of Medical Virology
Issue number11
StatePublished - Nov 2023

Bibliographical note

Publisher Copyright:
© 2023 The Authors. Journal of Medical Virology published by Wiley Periodicals LLC.


  • 3D genome organization
  • EBV

PubMed: MeSH publication types

  • Journal Article
  • Review
  • Research Support, N.I.H., Extramural


Dive into the research topics of 'Epstein-Barr virus and host cell 3D genome organization'. Together they form a unique fingerprint.

Cite this