Epstein-Barr Virus

Jennifer M Geris, Lauren M. Duval, Henry H. Balfour

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Scopus citations

Abstract

Epstein-Barr virus (EBV), a member of the herpesvirus family, infects at least 90% of the world's adults. While most infections are mild or asymptomatic, EBV causes or is a risk factor for a plethora of diseases including infectious mononucleosis, endemic Burkitt lymphoma, Hodgkin lymphoma, nasopharyngeal carcinoma, and multiple sclerosis. This article covers some basic virology, epidemiology, clinical manifestations, immune responses, diagnosis, prevention and treatment of EBV diseases. We also suggest future research priorities.

Original languageEnglish (US)
Title of host publicationEncyclopedia of Infection and Immunity
PublisherElsevier
Pages37-52
Number of pages16
Volume2
ISBN (Electronic)9780128187319
DOIs
StatePublished - Jan 1 2022

Bibliographical note

Publisher Copyright:
© 2022 Elsevier Inc. All rights reserved.

Keywords

  • EBV immune responses
  • EBV vaccine
  • Endemic Burkitt lymphoma
  • Epidemiology
  • Epstein-Barr virus
  • Gastric adenocarcinoma
  • Heterophile antibody
  • Hodgkin lymphoma
  • Human herpesvirus 4
  • Infectious mononucleosis
  • Nasopharyngeal carcinoma

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