Abstract
Epstein-Barr virus (EBV), a member of the herpesvirus family, infects at least 90% of the world's adults. While most infections are mild or asymptomatic, EBV causes or is a risk factor for a plethora of diseases including infectious mononucleosis, endemic Burkitt lymphoma, Hodgkin lymphoma, nasopharyngeal carcinoma, and multiple sclerosis. This article covers some basic virology, epidemiology, clinical manifestations, immune responses, diagnosis, prevention and treatment of EBV diseases. We also suggest future research priorities.
Original language | English (US) |
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Title of host publication | Encyclopedia of Infection and Immunity |
Publisher | Elsevier |
Pages | 37-52 |
Number of pages | 16 |
Volume | 2 |
ISBN (Electronic) | 9780128187319 |
DOIs | |
State | Published - Jan 1 2022 |
Bibliographical note
Publisher Copyright:© 2022 Elsevier Inc. All rights reserved.
Keywords
- EBV immune responses
- EBV vaccine
- Endemic Burkitt lymphoma
- Epidemiology
- Epstein-Barr virus
- Gastric adenocarcinoma
- Heterophile antibody
- Hodgkin lymphoma
- Human herpesvirus 4
- Infectious mononucleosis
- Nasopharyngeal carcinoma