Epistasis and hybrid sterility in Saccharomyces

Duncan Greig; Rhona H. Borts; Edward J. Louis; Michael Travisano

doi:10.1098/rspb.2002.1989

Epistasis and hybrid sterility in Saccharomyces

Duncan Greig, Rhona H. Borts, Edward J. Louis, Michael Travisano

Ecology, Evolution and Behavior

Research output: Contribution to journal › Article › peer-review

87 Scopus citations

Abstract

Hybrid sterility is thought to be due to deleterious epistatic interactions between genes from different species. Here we demonstrate that dominant genic incompatibility does not contribute to sterility in hybrids between Saccharomyces cerevisiae and five closely related species. Sterile diploids were made fertile by genome doubling to produce hybrid tetraploids. Based on these and previous results, we conclude that neither genic incompatibility nor classical chromosomal speciation models apply.

Original language	English (US)
Pages (from-to)	1167-1171
Number of pages	5
Journal	Proceedings of the Royal Society B: Biological Sciences
Volume	269
Issue number	1496
DOIs	https://doi.org/10.1098/rspb.2002.1989
State	Published - Jun 7 2002

Keywords

Evolution
Meiosis
Speciation
Tetraploid
Yeast

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AU - Louis, Edward J.

AU - Travisano, Michael

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KW - Meiosis

KW - Speciation

KW - Tetraploid

KW - Yeast

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Epistasis and hybrid sterility in Saccharomyces

Abstract

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