Epidemiology of the hemolytic uremic syndrome

Nevio Cimolai, James E. Carter, Michael J. Kovacs, William Cameron, Piero Ruggenenti, Giuseppe Remuzzi, Ennio C. Rossi, Dawn L. Martin, Kristine L. Macdonald, Michael T. Osterholm

Research output: Contribution to journalLetterpeer-review

9 Scopus citations


To the Editor: Martin et al. (Oct. 25 issue)1 emphasized the importance of verotoxigenic Escherichia coli as an etiologic agent in the hemolytic uremic syndrome. We have also studied E. coli O157:H7 infections with the purpose of defining risk factors for the progression of enteritis to the hemolytic uremic syndrome and have proposed that young age and the prolonged use of antimotility antidiarrheal agents may be risk factors.2,3 Do the authors have information about the use of drugs other than antibiotics by their patients? One point that needs clarification is the definition of antibiotic use.4 Many uses will be brief,.

Original languageEnglish (US)
Pages (from-to)1065-1066
Number of pages2
JournalNew England Journal of Medicine
Issue number15
StatePublished - Apr 11 1991


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