Eosinophilia and eosinophilic infiltration into splenic B-Cell high-grade lymphoma in a dog

Hirotaka Tomiyasu, Yasuhito Fujino, Jun Ugai, Yuko Goto-Koshino, Tetsuya Ide, Masashi Takahashi, Koichi Ohno, Kazuyuki Uchida, Hiroyuki Nakayama, Hajime Tsujimoto

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

A 13-year-old mixed-breed dog showing ascites, anorexia and anemia was found to have leukocytosis with marked eosinophilia, splenomegaly and hepatomegaly. The dog died 4 days after initial presentation and was diagnosed with splenic high-grade B-cell lymphoma at necropsy. Remarkable infiltrations of eosinophils were observed in spleen and liver tissues. The eosinophilia and infiltration of eosinophils into the lesions could have been associated with B-cell lymphoma because causes other than lymphoma were excluded. This is the first report of eosinophilia and eosinophilic infiltrations into neoplastic lesions in a dog with high-grade B-cell lymphoma.

Original languageEnglish (US)
Pages (from-to)1367-1370
Number of pages4
JournalJournal of Veterinary Medical Science
Volume72
Issue number10
DOIs
StatePublished - Oct 2010

Keywords

  • B-cell centroblastic lymphoma
  • Canine
  • Hypereosinophilia
  • Infiltration of eosinophils

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