Enzyme Mediated Synthesis of Stereoisomerically Pure α,ω-Diepoxides

Thomas R. Hoye; Lushi Tan

doi:10.1055/s-1996-5578

Enzyme Mediated Synthesis of Stereoisomerically Pure α,ω-Diepoxides

Thomas R. Hoye, Lushi Tan

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Abstract

The synthesis of stereoisomerically pure terminal diepoxides 2a and 2b was accomplished through enzyme catalyzed transesterification of bis(β-hydroxyalkyl)thioethers followed by S-alkylation and base promoted intramolecular displacement.

Original language	English (US)
Pages (from-to)	615-616
Number of pages	2
Journal	Synlett
Volume	1996
Issue number	7
DOIs	https://doi.org/10.1055/s-1996-5578
State	Published - Jan 1 1996

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title = "Enzyme Mediated Synthesis of Stereoisomerically Pure α,ω-Diepoxides",

abstract = "The synthesis of stereoisomerically pure terminal diepoxides 2a and 2b was accomplished through enzyme catalyzed transesterification of bis(β-hydroxyalkyl)thioethers followed by S-alkylation and base promoted intramolecular displacement.",

author = "Hoye, {Thomas R.} and Lushi Tan",

year = "1996",

month = jan,

day = "1",

doi = "10.1055/s-1996-5578",

language = "English (US)",

volume = "1996",

pages = "615--616",

journal = "Synlett",

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T1 - Enzyme Mediated Synthesis of Stereoisomerically Pure α,ω-Diepoxides

AU - Hoye, Thomas R.

AU - Tan, Lushi

PY - 1996/1/1

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N2 - The synthesis of stereoisomerically pure terminal diepoxides 2a and 2b was accomplished through enzyme catalyzed transesterification of bis(β-hydroxyalkyl)thioethers followed by S-alkylation and base promoted intramolecular displacement.

AB - The synthesis of stereoisomerically pure terminal diepoxides 2a and 2b was accomplished through enzyme catalyzed transesterification of bis(β-hydroxyalkyl)thioethers followed by S-alkylation and base promoted intramolecular displacement.

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U2 - 10.1055/s-1996-5578

DO - 10.1055/s-1996-5578

M3 - Article

AN - SCOPUS:0343776276

SN - 0936-5214

VL - 1996

SP - 615

EP - 616

JO - Synlett

JF - Synlett

IS - 7

ER -

Enzyme Mediated Synthesis of Stereoisomerically Pure α,ω-Diepoxides

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