Enzyme Mediated Synthesis of Stereoisomerically Pure α,ω-Diepoxides

Thomas R. Hoye, Lushi Tan

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

The synthesis of stereoisomerically pure terminal diepoxides 2a and 2b was accomplished through enzyme catalyzed transesterification of bis(β-hydroxyalkyl)thioethers followed by S-alkylation and base promoted intramolecular displacement.

Original languageEnglish (US)
Pages (from-to)615-616
Number of pages2
JournalSynlett
Volume1996
Issue number7
DOIs
StatePublished - Jan 1 1996

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