Abstract
A new ionic liquid, N-ethyl pyridinium trifluoroacetate, was used with a commercial protease to resolve N-acetyl amino acid esters in place of traditional organic solvents. Products with enantiomeric excess (ee) between 86-97% were obtained. These results show that with low concentration of this new ionic liquid, the enzymatic resolution can be increased considerably depending upon the substrate being used.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1257-1259 |
| Number of pages | 3 |
| Journal | Biotechnology Letters |
| Volume | 24 |
| Issue number | 15 |
| DOIs | |
| State | Published - 2002 |
| Externally published | Yes |
Keywords
- Alcalase
- Amino acid
- Enantiomer
- Enzymatic resolution
- Ionic liquid