Entamoeba histolytica infection in humans, chimpanzees and baboons in the Greater Gombe Ecosystem, Tanzania

Jessica R. Deere, Michele B. Parsons, Elizabeth V. Lonsdorf, Iddi Lipende, Shadrack Kamenya, D. Anthony Collins, Dominic A Travis, Thomas R. Gillespie

Research output: Contribution to journalArticle

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Abstract

Entamoeba histolytica is an enteric parasite that infects approximately 50 million people worldwide. Although E. histolytica is a zoonotic parasite that has the potential to infect nonhuman primates, such transmission is poorly understood. Consequently, this study examined whether E. histolytica is present among humans, chimpanzees and baboons living in the Greater Gombe Ecosystem (GGE), Tanzania. The primary aims were to determine patterns of E. histolytica infection in a system with human-nonhuman primate overlap and to test associations between infection status and potential risk factors of disease. Entamoeba spp. occurred in 60.3% of human, 65.6% of chimpanzee and 88.6% of baboon samples. Entamoeba histolytica occurred in 12.1% of human, 34.1% of chimpanzee and 10.9% of baboon samples. Human E. histolytica infection was associated with gastrointestinal symptoms. This was the first study to confirm the presence of E. histolytica in the GGE. The high sample prevalence of E. histolytica in three sympatric primates suggests that zoonotic transmission is possible and stresses the need for further phylogenetic studies. Interventions targeting better sanitation and hygiene practices for humans living in the GGE can help prevent E. histolytica infection in humans, while also protecting the endangered chimpanzees and other primates in this region.

Original languageEnglish (US)
Pages (from-to)1116-1122
Number of pages7
JournalParasitology
Volume146
Issue number9
DOIs
StatePublished - Aug 1 2019

Fingerprint

Entamoeba histolytica
Tanzania
Pan troglodytes
Papio
Ecosystem
ecosystems
Infection
infection
Primates
Zoonoses
Parasites
Entamoeba
parasites
Sanitation
sanitation
Hygiene
hygiene
sampling
signs and symptoms (animals and humans)
risk factors

Keywords

  • Amebiasis
  • diarrhoea
  • primates
  • protozoa
  • wildlife disease

PubMed: MeSH publication types

  • Journal Article

Cite this

Deere, J. R., Parsons, M. B., Lonsdorf, E. V., Lipende, I., Kamenya, S., Collins, D. A., ... Gillespie, T. R. (2019). Entamoeba histolytica infection in humans, chimpanzees and baboons in the Greater Gombe Ecosystem, Tanzania. Parasitology, 146(9), 1116-1122. https://doi.org/10.1017/S0031182018001397

Entamoeba histolytica infection in humans, chimpanzees and baboons in the Greater Gombe Ecosystem, Tanzania. / Deere, Jessica R.; Parsons, Michele B.; Lonsdorf, Elizabeth V.; Lipende, Iddi; Kamenya, Shadrack; Collins, D. Anthony; Travis, Dominic A; Gillespie, Thomas R.

In: Parasitology, Vol. 146, No. 9, 01.08.2019, p. 1116-1122.

Research output: Contribution to journalArticle

Deere, JR, Parsons, MB, Lonsdorf, EV, Lipende, I, Kamenya, S, Collins, DA, Travis, DA & Gillespie, TR 2019, 'Entamoeba histolytica infection in humans, chimpanzees and baboons in the Greater Gombe Ecosystem, Tanzania', Parasitology, vol. 146, no. 9, pp. 1116-1122. https://doi.org/10.1017/S0031182018001397
Deere JR, Parsons MB, Lonsdorf EV, Lipende I, Kamenya S, Collins DA et al. Entamoeba histolytica infection in humans, chimpanzees and baboons in the Greater Gombe Ecosystem, Tanzania. Parasitology. 2019 Aug 1;146(9):1116-1122. https://doi.org/10.1017/S0031182018001397
Deere, Jessica R. ; Parsons, Michele B. ; Lonsdorf, Elizabeth V. ; Lipende, Iddi ; Kamenya, Shadrack ; Collins, D. Anthony ; Travis, Dominic A ; Gillespie, Thomas R. / Entamoeba histolytica infection in humans, chimpanzees and baboons in the Greater Gombe Ecosystem, Tanzania. In: Parasitology. 2019 ; Vol. 146, No. 9. pp. 1116-1122.
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