Enolate and Other Carbon Nucleophile Alkylation Reactions using 1,2-Cyclic Sulfates as Terminal Epoxide Equivalents

Thomas R Hoye, Khushrav B. Crawford

Research output: Contribution to journalLetter

33 Scopus citations

Abstract

Enolates of esters and amides as well as α-sulfonyl-, α-cyano-, and α-phosphonyl-substituted anions react with cyclic sulfate 1 to give hydroxylated products arising from nucleophilic attack, on this terminal epoxide equivalent, at the primary carbon.

Original languageEnglish (US)
Pages (from-to)520-522
Number of pages3
JournalJournal of Organic Chemistry
Volume59
Issue number3
DOIs
StatePublished - Feb 1 1994

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