Enolate and Other Carbon Nucleophile Alkylation Reactions using 1,2-Cyclic Sulfates as Terminal Epoxide Equivalents

Thomas R Hoye, Khushrav B. Crawford

Research output: Contribution to journalLetterpeer-review

34 Scopus citations

Abstract

Enolates of esters and amides as well as α-sulfonyl-, α-cyano-, and α-phosphonyl-substituted anions react with cyclic sulfate 1 to give hydroxylated products arising from nucleophilic attack, on this terminal epoxide equivalent, at the primary carbon.

Original languageEnglish (US)
Pages (from-to)520-522
Number of pages3
JournalJournal of Organic Chemistry
Volume59
Issue number3
DOIs
StatePublished - Feb 1 1994

Fingerprint

Dive into the research topics of 'Enolate and Other Carbon Nucleophile Alkylation Reactions using 1,2-Cyclic Sulfates as Terminal Epoxide Equivalents'. Together they form a unique fingerprint.

Cite this