Campylobacter jejuni is a leading food-borne pathogen, and its antibiotic resistance is of serious concern to public health worldwide. C. jejuni is naturally competent for DNA transformation and freely takes up foreign DNA harboring genetic information responsible for antibiotic resistance. In this study, we demonstrate that C. jejuni transfers antibiotic resistance genes more frequently in biofilms than in planktonic cells by natural transformation.
Bibliographical notePublisher Copyright:
© 2014 American Society for Microbiology. All Rights Reserved. This study is supported by NSERC Discovery Grant 401843-2012-RGPIN and by intramural funding from the University of Alberta. Wethank Lynn McMullen and Michael Gänzle (University of Alberta) for sharing their laboratory facilities.