Enhanced transmission of antibiotic resistance in campylobacter jejuni biofilms by natural transformation

Junghee Bae, Euna Oh, Byeonghwa Jeon

Research output: Contribution to journalArticlepeer-review

49 Scopus citations

Abstract

Campylobacter jejuni is a leading food-borne pathogen, and its antibiotic resistance is of serious concern to public health worldwide. C. jejuni is naturally competent for DNA transformation and freely takes up foreign DNA harboring genetic information responsible for antibiotic resistance. In this study, we demonstrate that C. jejuni transfers antibiotic resistance genes more frequently in biofilms than in planktonic cells by natural transformation.

Original languageEnglish (US)
Pages (from-to)7573-7575
Number of pages3
JournalAntimicrobial agents and chemotherapy
Volume58
Issue number12
DOIs
StatePublished - Dec 1 2014
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2014 American Society for Microbiology. All Rights Reserved. This study is supported by NSERC Discovery Grant 401843-2012-RGPIN and by intramural funding from the University of Alberta. Wethank Lynn McMullen and Michael Gänzle (University of Alberta) for sharing their laboratory facilities.

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