Engineering of secondary metabolite pathways

Benjamin N. Mijts, Claudia Schmidt-Dannert

Research output: Contribution to journalReview articlepeer-review

51 Scopus citations

Abstract

Nature produces an astonishing wealth of secondary metabolites with important biological functions. To access this diversity of structurally complex chemical compounds for industrial and biomedical applications, cells have been engineered to produce higher levels and/or novel compounds that were previously inaccessible. Recent examples of metabolic and combinatorial engineering illustrate different strategies for the production of secondary metabolites in microbial cells.

Original languageEnglish (US)
Pages (from-to)597-602
Number of pages6
JournalCurrent opinion in biotechnology
Volume14
Issue number6
DOIs
StatePublished - Dec 2003

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