TY - JOUR
T1 - Endotracheal tube cuff lidocaine is not superior to intravenous lidocaine in short pediatric surgeries
AU - Behzadi, Mehrdad
AU - Hajimohamadi, Fatemeh
AU - Alagha, Afshar Etemadi
AU - Abouzari, Mehdi
AU - Rashidi, Armin
N1 - Copyright:
Copyright 2010 Elsevier B.V., All rights reserved.
PY - 2010/5
Y1 - 2010/5
N2 - Background: Instillation of lidocaine into the endotracheal tube cuff is a method with reported efficiency in promoting a smoother emergence from anesthesia with endotracheal intubation. However, whether or not this method is helpful in children and in surgeries with short duration has not been investigated previously. Methods: 176 ASA I-II children undergoing adenotonsillectomy were enrolled in this prospective, double-blind, randomized clinical trial. Patients were randomly allocated to two groups. Patients in the ECL group (n=88) were injected 2% lidocaine into their endotracheal tube cuff and received saline (1.5mg/kg) intravenously. The IVL group (n=88) received 1.5mg/kg of 2% lidocaine intravenously and saline into the endotracheal tube cuff. In both groups, intra-cuff injections were initiated immediately after insertion of the endotracheal tube and terminated before the cuff pressure reached 20cmH2O. The parameters measured were: coughing (graded by a scale of 3 at the time of extubation), systolic and diastolic blood pressures and heart rate (from the time of extubation up to 5min after extubation at 1-min intervals), and laryngospasm (defined as the presence of hoarseness or absence of airflow). Results: The groups were not different in sex, age, weight, height, body mass index, anesthesia duration, and baseline hemodynamic parameters. The grade of coughing was significantly higher in the ECL group. The incidence of laryngospasm and hemodynamic trends did not differ between the groups. Conclusions: Our results indicate that intra-cuff lidocaine may not be beneficial in children and in surgeries with a short duration.
AB - Background: Instillation of lidocaine into the endotracheal tube cuff is a method with reported efficiency in promoting a smoother emergence from anesthesia with endotracheal intubation. However, whether or not this method is helpful in children and in surgeries with short duration has not been investigated previously. Methods: 176 ASA I-II children undergoing adenotonsillectomy were enrolled in this prospective, double-blind, randomized clinical trial. Patients were randomly allocated to two groups. Patients in the ECL group (n=88) were injected 2% lidocaine into their endotracheal tube cuff and received saline (1.5mg/kg) intravenously. The IVL group (n=88) received 1.5mg/kg of 2% lidocaine intravenously and saline into the endotracheal tube cuff. In both groups, intra-cuff injections were initiated immediately after insertion of the endotracheal tube and terminated before the cuff pressure reached 20cmH2O. The parameters measured were: coughing (graded by a scale of 3 at the time of extubation), systolic and diastolic blood pressures and heart rate (from the time of extubation up to 5min after extubation at 1-min intervals), and laryngospasm (defined as the presence of hoarseness or absence of airflow). Results: The groups were not different in sex, age, weight, height, body mass index, anesthesia duration, and baseline hemodynamic parameters. The grade of coughing was significantly higher in the ECL group. The incidence of laryngospasm and hemodynamic trends did not differ between the groups. Conclusions: Our results indicate that intra-cuff lidocaine may not be beneficial in children and in surgeries with a short duration.
KW - Children
KW - Coughing
KW - Endotracheal
KW - Hemodynamic
KW - Laryngospasm
KW - Lidocaine
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U2 - 10.1016/j.ijporl.2010.01.025
DO - 10.1016/j.ijporl.2010.01.025
M3 - Article
C2 - 20189659
AN - SCOPUS:77951649063
SN - 0165-5876
VL - 74
SP - 486
EP - 488
JO - International Journal of Pediatric Otorhinolaryngology
JF - International Journal of Pediatric Otorhinolaryngology
IS - 5
ER -