Endotracheal tube cuff lidocaine is not superior to intravenous lidocaine in short pediatric surgeries

Mehrdad Behzadi, Fatemeh Hajimohamadi, Afshar Etemadi Alagha, Mehdi Abouzari, Armin Rashidi

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


Background: Instillation of lidocaine into the endotracheal tube cuff is a method with reported efficiency in promoting a smoother emergence from anesthesia with endotracheal intubation. However, whether or not this method is helpful in children and in surgeries with short duration has not been investigated previously. Methods: 176 ASA I-II children undergoing adenotonsillectomy were enrolled in this prospective, double-blind, randomized clinical trial. Patients were randomly allocated to two groups. Patients in the ECL group (n=88) were injected 2% lidocaine into their endotracheal tube cuff and received saline (1.5mg/kg) intravenously. The IVL group (n=88) received 1.5mg/kg of 2% lidocaine intravenously and saline into the endotracheal tube cuff. In both groups, intra-cuff injections were initiated immediately after insertion of the endotracheal tube and terminated before the cuff pressure reached 20cmH2O. The parameters measured were: coughing (graded by a scale of 3 at the time of extubation), systolic and diastolic blood pressures and heart rate (from the time of extubation up to 5min after extubation at 1-min intervals), and laryngospasm (defined as the presence of hoarseness or absence of airflow). Results: The groups were not different in sex, age, weight, height, body mass index, anesthesia duration, and baseline hemodynamic parameters. The grade of coughing was significantly higher in the ECL group. The incidence of laryngospasm and hemodynamic trends did not differ between the groups. Conclusions: Our results indicate that intra-cuff lidocaine may not be beneficial in children and in surgeries with a short duration.

Original languageEnglish (US)
Pages (from-to)486-488
Number of pages3
JournalInternational Journal of Pediatric Otorhinolaryngology
Issue number5
StatePublished - May 2010


  • Children
  • Coughing
  • Endotracheal
  • Hemodynamic
  • Laryngospasm
  • Lidocaine


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