Endophenotypes in psychiatric disease: Prospects and challenges

William G. Iacono

doi:10.1186/s13073-018-0526-5

Endophenotypes in psychiatric disease: Prospects and challenges

William G. Iacono

Psychology (Twin Cities)

Research output: Contribution to journal › Comment/debate › peer-review

27 Scopus citations

Abstract

Endophenotypes, quantitative neurobehavioral traits that index genetic susceptibility for a psychiatric disorder, have been examined in thousands of studies. Nevertheless, they have underexploited potential to provide etiological insights into prognosis, how psychopathology develops, the etiology of comorbidity, and the mechanisms of gene function.

Original language	English (US)
Article number	11
Journal	Genome medicine
Volume	10
Issue number	1
DOIs	https://doi.org/10.1186/s13073-018-0526-5
State	Published - Feb 22 2018

Bibliographical note

Funding Information:
Salary support was provided by National Institute on Drug Abuse grants DA005147 and DA036216

Publisher Copyright:
© 2018 The Author(s).

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10.1186/s13073-018-0526-5

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Endophenotypes in psychiatric disease: Prospects and challenges

Abstract

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