Endemic mycosis complicating human immunodeficiency virus infection

george a sarosi, Scott F Davies

Research output: Contribution to journalArticlepeer-review

22 Scopus citations


Persons infected with the human immunodeficiency virus are prone to the development of many fungal diseases. Normal hosts with intact immunity usually recover from infection by these less-invasive fungi. In persons with compromised T-cell-mediated immunity, however, widespread dissemination from a pulmonary focus occurs. In this review, we discuss the epidemiology, clinical manifestations, diagnosis, and treatment of the three major North American mycoses, histoplasmosis, blastomycosis, and coccidioidomycosis. In most cases, amphotericin B is the initial drug of choice, followed by one of the azoles for lifelong maintenance therapy.

Original languageEnglish (US)
Pages (from-to)335-340
Number of pages6
JournalWestern Journal of Medicine
Issue number4
StatePublished - Apr 1996


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