End of the road: Astrocyte endfeet regulate OPC migration and myelination

Greg J. Duncan; Ben Emery

doi:10.1016/j.neuron.2022.12.023

End of the road: Astrocyte endfeet regulate OPC migration and myelination

Greg J. Duncan
, Ben Emery

Research output: Contribution to journal › Comment/debate › peer-review

5 Scopus citations

Abstract

Oligodendrocyte precursor cells (OPCs) use the vasculature as a scaffold for their migration. In this issue of Neuron, Su et al. determine that astrocytic ensheathment of the vasculature mediates OPC detachment from blood vessels via the secretion of semaphorins, regulating the timing of oligodendrocyte differentiation.

Original language	English (US)
Pages (from-to)	139-141
Number of pages	3
Journal	Neuron
Volume	111
Issue number	2
DOIs	https://doi.org/10.1016/j.neuron.2022.12.023
State	Published - Jan 18 2023
Externally published	Yes

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© 2022 Elsevier Inc.

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10.1016/j.neuron.2022.12.023

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title = "End of the road: Astrocyte endfeet regulate OPC migration and myelination",

abstract = "Oligodendrocyte precursor cells (OPCs) use the vasculature as a scaffold for their migration. In this issue of Neuron, Su et al. determine that astrocytic ensheathment of the vasculature mediates OPC detachment from blood vessels via the secretion of semaphorins, regulating the timing of oligodendrocyte differentiation.",

author = "Duncan, \{Greg J.\} and Ben Emery",

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year = "2023",

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day = "18",

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language = "English (US)",

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AU - Emery, Ben

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N2 - Oligodendrocyte precursor cells (OPCs) use the vasculature as a scaffold for their migration. In this issue of Neuron, Su et al. determine that astrocytic ensheathment of the vasculature mediates OPC detachment from blood vessels via the secretion of semaphorins, regulating the timing of oligodendrocyte differentiation.

AB - Oligodendrocyte precursor cells (OPCs) use the vasculature as a scaffold for their migration. In this issue of Neuron, Su et al. determine that astrocytic ensheathment of the vasculature mediates OPC detachment from blood vessels via the secretion of semaphorins, regulating the timing of oligodendrocyte differentiation.

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UR - https://www.scopus.com/pages/publications/85146331499#tab=citedBy

U2 - 10.1016/j.neuron.2022.12.023

DO - 10.1016/j.neuron.2022.12.023

M3 - Comment/debate

C2 - 36657394

AN - SCOPUS:85146331499

SN - 0896-6273

VL - 111

SP - 139

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JO - Neuron

JF - Neuron

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ER -

End of the road: Astrocyte endfeet regulate OPC migration and myelination

Abstract

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