Enantiomer-specific in vitro biotransformation of select pharmaceuticals in rainbow trout (oncorhynchus mykiss)

Keyphrases

• Trout 100%
• Metabolism 100%
• Stereospecific 100%
• Clearance Rate 100%
• Racemic Mixture 100%
• Rainbow Trout Oncorhynchus Mykiss 100%
• Relative Clearance 100%
• Substrate Depletion 100%
• In Vitro Biotransformation 100%
• Pharmacokinetics 50%
• Environmental Studies 50%
• Biotransformation 50%
• Wildlife 50%
• Emerging Concern 50%
• Propranolol 50%
• Species Differences 50%
• Chirality 50%
• Human Data 50%
• In Vitro Metabolism 50%
• R-enantiomer 50%
• Fluoxetine 50%
• Relative Toxicity 50%
• Hepatic Clearance 50%
• Liver S9 50%
• Rainbow Trout 50%
• Environmentally Relevant 50%
• Pharmaceuticals in the Environment 50%
• Interspecies Extrapolation 50%
• Chiral Drugs 50%
• Depletion Curves 50%
• Biomedical Studies 50%
• Chiral Compounds 50%
• Inactive Control 50%

Pharmacology, Toxicology and Pharmaceutical Science

• Oncorhynchus mykiss 100%
• Salmonine 66%
• Propranolol 33%
• Ibuprofen 33%
• Fluoxetine 33%
• Pharmacokinetics 33%