Enalapril alone and in combination with hydrochlorothiazide in the treatment of hypertension: Effect on treadmill exercise performance

A. S. Leon, C. McNally, D. Casal

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

Enalapril, a new angiotensin-converting-enzyme inhibitor, was more effective when combined with hydrochlorothiazide than either drug alone in controlling moderate hypertension over a 16-week period in 20 middle-aged men and women. Fifteen of these subjects underwent progressive treadmill exercise tests at baseline while receiving placebo and after blood pressure control was achieved. Systolic blood pressure response to submaximal and near-maximal exercise was significantly lower during treatment. However, there was no significant effect during exercise on heart rate, perceived exertion, respiratory exchange ratio, exercise test duration, or oxygen uptake.

Original languageEnglish (US)
Pages (from-to)251-259
Number of pages9
JournalJournal of Cardiopulmonary Rehabilitation
Volume6
Issue number7
DOIs
StatePublished - Jan 1 1986

Fingerprint

Dive into the research topics of 'Enalapril alone and in combination with hydrochlorothiazide in the treatment of hypertension: Effect on treadmill exercise performance'. Together they form a unique fingerprint.

Cite this