Employing arynes in transition-metal-free monoarylation of aromatic tertiary amines

Sachin Suresh Bhojgude; Trinadh Kaicharla; Akkattu T. Biju

doi:10.1021/ol4029258

Employing arynes in transition-metal-free monoarylation of aromatic tertiary amines

Sachin Suresh Bhojgude
, Trinadh Kaicharla
, Akkattu T. Biju

Research output: Contribution to journal › Article › peer-review

74 Scopus citations

Abstract

The highly monoselective N-arylation of aromatic tertiary amines using a transition-metal-free approach using arynes has been developed. The reaction afforded functionalized diaryl amines in moderate to excellent yield. High levels of functional group compatibility especially with halogen containing substrates, dyes and donor-acceptor systems, and high yields of products are the notable features of the present reaction.

Original language	English (US)
Pages (from-to)	5452-5455
Number of pages	4
Journal	Organic Letters
Volume	15
Issue number	21
DOIs	https://doi.org/10.1021/ol4029258
State	Published - Nov 1 2013
Externally published	Yes

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10.1021/ol4029258

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title = "Employing arynes in transition-metal-free monoarylation of aromatic tertiary amines",

abstract = "The highly monoselective N-arylation of aromatic tertiary amines using a transition-metal-free approach using arynes has been developed. The reaction afforded functionalized diaryl amines in moderate to excellent yield. High levels of functional group compatibility especially with halogen containing substrates, dyes and donor-acceptor systems, and high yields of products are the notable features of the present reaction.",

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AU - Biju, Akkattu T.

PY - 2013/11/1

Y1 - 2013/11/1

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AB - The highly monoselective N-arylation of aromatic tertiary amines using a transition-metal-free approach using arynes has been developed. The reaction afforded functionalized diaryl amines in moderate to excellent yield. High levels of functional group compatibility especially with halogen containing substrates, dyes and donor-acceptor systems, and high yields of products are the notable features of the present reaction.

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JO - Organic Letters

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Employing arynes in transition-metal-free monoarylation of aromatic tertiary amines

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