Emerging Systemic Therapies for the Management of Penile Cancer

Shilpa Gupta, Guru Sonpavde

Research output: Contribution to journalReview articlepeer-review

11 Scopus citations


Penile squamous cell carcinoma (PSCC) is a rare cancer, but is more common in developing countries. Locally advanced and metastatic PSCC is associated with significant morbidity and mortality, with the prognosis remaining extremely poor. The authors searched PubMed and published abstracts for metastatic PSCC studies to describe emerging therapies. Multimodality treatment using chemotherapy, radiation, and consolidative surgery are standard of care. Utilizing anti-EGFR therapies and novel immunotheraputic approaches may help improve outcomes in PSCC.

Original languageEnglish (US)
Pages (from-to)481-491
Number of pages11
JournalUrologic Clinics of North America
Issue number4
StatePublished - Nov 1 2016

Bibliographical note

Publisher Copyright:
© 2016 Elsevier Inc.


  • Chemotherapy
  • Combined modality therapy
  • EGFR
  • PD-1
  • Penile squamous cell carcinoma
  • Targeted therapy
  • VEGF


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