Abstract
A vast majority of the human genome encodes long non-coding RNAs (lncRNAs) as compared to protein-coding genes (PCGs). But most efforts to determine biomarkers of anticancer drug response have focused entirely on PCGs. Comprehensive investigation of lncRNAs and drug response demonstrates that lncRNAs are indeed crucial biomarkers of drug response.
Original language | English (US) |
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Article number | 1684130 |
Journal | Molecular and Cellular Oncology |
Volume | 7 |
Issue number | 1 |
DOIs | |
State | Published - Jan 2 2020 |
Bibliographical note
Funding Information:This work was supported by the National Cancer Institute [R01CA204856].
Publisher Copyright:
© 2019, © 2019 Taylor & Francis Group, LLC.
Keywords
- Long non-coding RNA
- drug response prediction
- pharmacogenomics