Emergency department management of thyrotoxic crisis with esmolol

Douglas D. Brunette, Carole Rothong

Research output: Contribution to journalArticlepeer-review

39 Scopus citations


A previously healthy 26-year-old woman presented to the emergency department complaining of a severe, throbbing, and bifrontal headache. Initial vital signs were pulse rate, 130 beats/min; blood pressure, 128 50 mm Hg; temperature, 100.1°F. Shortly thereafter the patient's pulse and temperature increased to 170 beats/min and 103°F, respectively. Physical examination showed a tremulous, anxious woman in moderate distress who had a diffusely and symmetrically enlarged thyroid gland. A diagnosis of thyrotoxic crisis was made, and appropriate therapy instituted, including the use of an esmolol infusion for control of hypersympathetic activity. A review of the clinical presentation, diagnosis, and management of thyrotoxic crisis is presented.

Original languageEnglish (US)
Pages (from-to)232-234
Number of pages3
JournalAmerican Journal of Emergency Medicine
Issue number3
StatePublished - May 1991
Externally publishedYes


  • Esmolol
  • Graves disease
  • thyroid
  • thyroid storm
  • thyrotoxic crisis


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