Abstract
Surveillance of antibiotic resistance of Salmonella isolates from humans in the north-eastern United States has detected resistance to chloramphenicol on 8 occasions, three of which were hospital outbreaks. Resistance was developed during treatment in 5 instances, and in another instance this situation was suspected. On 2 other occasions chloramphenicol-resistant Salmonella appear to have been imported from outside the country. Common features of the cases were multiple antibiotic resistance, transfer of R-factor, simultaneous presence of different patterns of resistance, similar patterns of antibiotic resistance in other intestinal bacteria, and apparent in vivo and in vitro loss of resistance to chloramphenicol with time.
| Original language | Undefined/Unknown |
|---|---|
| Pages (from-to) | 807-812 |
| Number of pages | 6 |
| Journal | Journal of Infectious Diseases |
| Volume | 135 |
| Issue number | 5 |
| State | Published - 1977 |
Keywords
- antibiotic resistance
- drug resistance
- geographic distribution
- hospital infection
- microorganism
- R factor
- Salmonella
- salmonella albany
- salmonella goettingen
- salmonella typhimurium
- theoretical study
- ampicillin
- carbenicillin
- cefalotin
- chloramphenicol
- cotrimoxazole
- gentamicin
- kanamycin
- streptomycin
- sulfafurazole
- tetracycline