Elevated APOBEC3B expression drives a kataegic-like mutation signature and replication stress-related therapeutic vulnerabilities in p53-defective cells

Jenni Nikkilä, Rahul Kumar, James Campbell, Inger Brandsma, Helen N. Pemberton, Fredrik Wallberg, Kinga Nagy, Ildikó Scheer, Beata G. Vertessy, Artur A. Serebrenik, Valentina Monni, Reuben S. Harris, Stephen J. Pettitt, Alan Ashworth, Christopher J. Lord

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Medicine & Life Sciences