Electrostatically Enhanced Thioureas

Yang Fan, Steven R Kass

Research output: Contribution to journalArticlepeer-review

27 Scopus citations

Abstract

A new class of readily prepared thiourea catalysts with one or more positively charged centers and no new hydrogen-bonding sites are exploited in several bond-forming reactions and are orders of magnitude more reactive than Schreiner's thiourea. These findings provide the basis for a new strategy for activating hydrogen-bond catalysts.

Original languageEnglish (US)
Pages (from-to)188-191
Number of pages4
JournalOrganic Letters
Volume18
Issue number2
DOIs
StatePublished - Jan 15 2016

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