Abstract
Treatment of psoriasis with psoralens and high-intensity long-wave ultraviolet light (PUVA) produces changes in the ultrastructure of elastic tissue in skin. Early alterations consist of a loss of elastin followed by a breakdown of the microfibrils and subsequent fragmentation of the elastic fiber. Tissue examined 15 months after treatment was stopped still showed marked ultrastructural changes in the elastic fibers.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 186-192 |
| Number of pages | 7 |
| Journal | Journal of the American Academy of Dermatology |
| Volume | 3 |
| Issue number | 2 |
| DOIs | |
| State | Published - Jan 1 1980 |
| Externally published | Yes |
Bibliographical note
Funding Information:Supported by United States Public Health Service Grant 1 ROI-AM-21681, lips Foundatoni and the McKnight Foundonati.