Efficient Editing of the CXCR4 Locus Using Cas9 Ribonucleoprotein Complexes Stabilized with Polyglutamic Acid

Keyphrases

• C-X-C Chemokine Receptor Type 4 (CXCR4) 100%
• Poly-γ-glutamic Acid (γ-PGA) 100%
• Ribonucleoprotein Complex 100%
• Cas9 Ribonucleoprotein 100%
• Fold Increase 66%
• Gene Therapy 33%
• HIV Infection 33%
• Knock-in Mouse Model 33%
• Human Disease 33%
• Gene Editing 33%
• Genome Editing 33%
• Cas9 Protein 33%
• Peptide Inhibitor 33%
• CRISPR-Cas9 System 33%
• T Cell Lines 33%
• CD4+ T Lymphocytes 33%
• Efficiency Improvement 33%
• HIV-1 Fusion Peptide 33%
• Guide RNA (gRNA) 33%

Medicine and Dentistry

• Cas9 100%
• Ribonucleoprotein 100%
• Polyglutamic Acid 100%
• Gene Therapy 25%
• T Cell 25%
• Human Immunodeficiency Virus Infection 25%
• Human Immunodeficiency Virus 25%
• Clustered Regularly Interspaced Short Palindromic Repeat 25%
• Glutamic Acid 25%
• CD4+ T Lymphocyte 25%
• Guide RNA 25%
• Genome Editing 25%
• Cell Line 25%
• Diseases 25%
• Peptide 25%

Pharmacology, Toxicology and Pharmaceutical Science

• Ribonucleoprotein 100%
• Polyglutamic Acid 100%
• HIV 50%
• Human Immunodeficiency Virus Infection 50%
• Guide RNA 50%
• Glutamic Acid 50%
• Diseases 50%
• Peptide 50%