Abstract
Smokers were randomly assigned to 0, 7, 14 or 21 mg doses of transdermal nicotine and had their eating and weight followed for 6 weeks. Among the 66 subjects who were abstinent for all 6 weeks, caloric, carbohydrate and fat intake, hunger, and weight increased in those on placebo, but alcohol, caffeine and protein intake did not. Nicotine patch decreased caloric, carbohydrate and fat intake in a dose-related manner, showed a trend for weight and showed no effect for hunger. Neither abstinence from smoking nor nicotine therapy shifted the percent of calories from sweets or carbohydrates. We conclude nicotine replacement reduces post-cessation increases in eating but does not have a specific effect on sweet intake.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 151-159 |
| Number of pages | 9 |
| Journal | Journal of substance abuse |
| Volume | 9 |
| Issue number | 1 |
| DOIs | |
| State | Published - 1997 |
Bibliographical note
Funding Information:ACKNOWLEDGMENTS: This study was funded by a grant from Hoechst Marion Roussel, by Research Scientist DevelopmentA ward DA-00109 (JRH) and by P50DA-09259( DKH) from the NationalI nstituteo n Drug Abuse.T he authorsw ish to thank Peter Callas for statisticalh elp.