Effects of Phenethyl Isothiocyanate on the Tissue Distribution of 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone and Metabolites in F344 Rats

Keyphrases

• Tissue Distribution 100%
• Phenethyl Isothiocyanate (PEITC) 100%
• 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone 100%
• F344 Rats 100%
• Hydroxylation 36%
• Lung 27%
• Nasal mucosa 27%
• Liver 18%
• Oncogenesis 9%
• Pancreas 9%
• Kidney 9%
• Metabolism 9%
• N-nitrosamines 9%
• Lung Tumorigenesis 9%
• Lung Tumor 9%
• Area under the Curve 9%
• Carbonyl Reduction 9%
• Multiple Injections 9%
• Metabolic Activation 9%
• Stomach 9%
• Treatment Control 9%
• Tumor Induction 9%
• Tissue Metabolites 9%
• Lung mucosa 9%
• Tumor Inhibition 9%
• Butanone 9%
• Feeding Control 9%

Pharmacology, Toxicology and Pharmaceutical Science

• NNK 100%
• Fischer 344 Rat 100%
• Phenethyl Isothiocyanate 100%
• 4 (Methylnitrosamino) 1 (3 Pyridyl) 1 Butanone 100%
• Carcinogenesis 15%
• Rat 10%
• Tobacco-Specific Nitrosamines 5%
• Lung Tumor 5%
• Cancer Inhibition 5%
• 2 Butanone 5%
• 4 (Methylnitrosamino) 1 (3 Pyridyl) 1 Butanol 5%