Abstract
The effects of phencyclidine were assessed under two distinctive paradigms. In a traditional laboratory assay where pairs of rats received intermittent foot shocks, phencyclidine at doses of 0.5 to 2.0 mg/kg decreased the number of shock-elicited fighting bouts in dose-dependent fashion. Similar dose-dependent decreases in biting were also observed under a procedure where single restrained rats received intermittent tail shocks, which evoked biting of an inanimate target.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 813-818 |
| Number of pages | 6 |
| Journal | Pharmacology, Biochemistry and Behavior |
| Volume | 15 |
| Issue number | 5 |
| DOIs | |
| State | Published - Nov 1981 |
Keywords
- Biting
- Phencyclidine
- Rats
- Shock-induced aggression