The effects of phencyclidine were assessed under two distinctive paradigms. In a traditional laboratory assay where pairs of rats received intermittent foot shocks, phencyclidine at doses of 0.5 to 2.0 mg/kg decreased the number of shock-elicited fighting bouts in dose-dependent fashion. Similar dose-dependent decreases in biting were also observed under a procedure where single restrained rats received intermittent tail shocks, which evoked biting of an inanimate target.
|Original language||English (US)|
|Number of pages||6|
|Journal||Pharmacology, Biochemistry and Behavior|
|State||Published - Nov 1981|
- Shock-induced aggression