By the combined determination of LDH and isoenzymes in rat plasma, the degree and extent of training required to prevent the marked rise of enzymatic activity associated with exercise was investigated. Training by swimming 1 hr daily for 1-10 weeks provided little or partial protection against severe exercise. Training 4 hr daily for 6-8 weeks prevented the enzymatic changes observed after severe exercise. By isoenzyme analysis the rise of plasma LDH activity was associaed with the kidney, heart, liver, and muscle; they further showed that adaptation to exercise by training varied in the different organs.
|Number of pages
|Proceedings of the Society for Experimental Biology and Medicine
|Published - Oct 1968