TY - JOUR
T1 - Effects of autogenic training and antihypertensive agents on circadian and circaseptan variation of blood pressure
AU - Watanabe, Yoshihiko
AU - Cornelissen-Guillaume, Germaine G
AU - Watanabe, Misako
AU - Watanabe, Fumihiko
AU - Otsuka, Kuniaki
AU - Ohkawa, Shi Ichiro
AU - Kikuchi, Takenori
AU - Halberg, Franz
PY - 2003/10
Y1 - 2003/10
N2 - Even when the daily blood pressure mean is acceptable, too large a circadian amplitude of blood pressure largely increases cardiovascular disease risk. Autogenic training (N = 11), a non-pharmacologic intervention capable of lowering an excessive blood pressure variability, may be well-suited for MESOR-normotensive patients diagnosed with circadian-hyper-amplitude-tension (CHAT). Not all anti-hypertensive drugs affect blood pressure variability. Accordingly, long-acting carteolol (N = 11) and/or atenolol (N = 8) may be preferred to captopril retard (N = 13), nilvadipine (N = 8), or amlodipine (N = 7) for midline-estimating statistic of rhythm (MESOR)-hypertensive patients with CHAT. Prospective outcome studies are needed to assess whether the relative merits of these treatments are in keeping with their effects on blood pressure and blood pressure variability.
AB - Even when the daily blood pressure mean is acceptable, too large a circadian amplitude of blood pressure largely increases cardiovascular disease risk. Autogenic training (N = 11), a non-pharmacologic intervention capable of lowering an excessive blood pressure variability, may be well-suited for MESOR-normotensive patients diagnosed with circadian-hyper-amplitude-tension (CHAT). Not all anti-hypertensive drugs affect blood pressure variability. Accordingly, long-acting carteolol (N = 11) and/or atenolol (N = 8) may be preferred to captopril retard (N = 13), nilvadipine (N = 8), or amlodipine (N = 7) for midline-estimating statistic of rhythm (MESOR)-hypertensive patients with CHAT. Prospective outcome studies are needed to assess whether the relative merits of these treatments are in keeping with their effects on blood pressure and blood pressure variability.
KW - Blood pressure variability
KW - CHAT (circadian-hyper-amplitude-tension)
KW - Cardiovascular disease risk
KW - Non-pharmacologic vs. pharmacologic intervention
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U2 - 10.1081/CEH-120024984
DO - 10.1081/CEH-120024984
M3 - Article
C2 - 14596365
AN - SCOPUS:0141676234
SN - 1064-1963
VL - 25
SP - 405
EP - 412
JO - Clinical and Experimental Hypertension
JF - Clinical and Experimental Hypertension
IS - 7
ER -