Effects of an allicin-based product on cryptosporidiosis in neonatal calves

Erik J. Olson, William B. Epperson, David H. Zeman, Ronald Fayer, Michael B. Hildreth

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


Objective - To evaluate effectiveness of an allicin-based product in neonatal calves inoculated with Cryptosporidium parvum. Design - Randomized controlled study. Animals - 43 neonatal calves. Procedure - Calves were inoculated with 1.5 x 106 or 7.5 x 106 C parvum oocysts within 2 days after birth. Calves were given an allicin-based product once after inoculation or daily for 7 days after inoculation or were not treated. Calves that developed diarrhea were treated by administration of the product. Fecal consistency scores and weight gains were statistically evaluated. Results - Mean daily weight gain and severity of diarrhea in calves 4 to 21 days old were unaffected by prophylactic use of the product. However, intensive prophylactic administration may have delayed onset of C parvum-induced diarrhea in calves inoculated with the lower dose of oocysts. Clinical Implications - Administration of an allicin-based product did not alter duration of C parvum-induced diarrhea or enhance weight gain in neonatal calves. However, intensive prophylactic administration of an allicin-based product may delay onset of diarrhea in calves exposed to C parvum oocysts.

Original languageEnglish (US)
Pages (from-to)987-990
Number of pages4
JournalJournal of the American Veterinary Medical Association
Issue number7
StatePublished - Apr 1 1998


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